Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13360008 | 0.92 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL11060407 | 0.91 | ALDH1A1 (0.64) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL29671333 | 0.85 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL16859557 | 0.85 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL14072102 | 0.85 | KDM4E (0.69) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL30239539 | 0.84 | TSHR (0.70) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL20897156 | 0.84 | TSHR (0.70) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL62565 | 0.84 | TSHR (0.80) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL29421150 | 0.84 | TSHR (0.80) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL4465565 | 0.84 | CDC25B (0.69) | TSHRALDH1A1HSD17B10KDM4ECDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448869-A | HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-15 | — | — | US | claimed |
| US-4542203-A | Method for producing branched aromatic polyesters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-09-17 | — | — | US | disclosed |
| US-4448869-A | HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |