Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10961102 | 0.91 | TSHR (0.66) | ALDH1A1CDC25BTSHRTDP1L3MBTL1 | |
| SCHEMBL4465565 | 0.87 | CDC25B (0.69) | ALDH1A1CDC25BTSHRKDM4EHSD17B10 | |
| SCHEMBL28754866 | 0.84 | ALDH1A1 (0.75) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL5788119 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL39575 | 0.83 | ALDH1A1 (0.79) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL31490936 | 0.83 | ALDH1A1 (0.79) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL2117339 | 0.82 | ALDH1A1 (0.71) | ALDH1A1CDC25BTSHRTDP1L3MBTL1 | |
| SCHEMBL10880068 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL28250478 | 0.82 | ALDH1A1 (0.66) | ALDH1A1CDC25BTSHRTDP1L3MBTL1 | |
| SCHEMBL15113881 | 0.82 | CDC25B (0.47) | ALDH1A1CDC25BTSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448869-A | HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-15 | — | — | US | claimed |
| US-4448869-A | HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |