Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115941 | 0.78 | AXL (0.53) | MAOBALDH1A1PIK3CAMTORPIK3CG | |
| SCHEMBL9667797 | 0.77 | MAOB (0.57) | MAOB | |
| SCHEMBL10800665 | 0.76 | ALDH1A1 (0.44) | MAOBALDH1A1PIK3CAMTORPIK3CG | |
| SCHEMBL10804898 | 0.75 | ALDH1A1 (0.43) | MAOBALDH1A1PIK3CAMTORPIK3CG | |
| SCHEMBL22288623 | 0.74 | MAOB (0.63) | MAOB | |
| SCHEMBL10806139 | 0.73 | MAOB (0.56) | MAOB | |
| SCHEMBL22304501 | 0.72 | MAOB (0.63) | MAOB | |
| SCHEMBL8683790 | 0.72 | MAOB (0.83) | MAOB | |
| SCHEMBL7287552 | 0.72 | MAOB (0.61) | MAOB | |
| SCHEMBL7288118 | 0.72 | PDE3B (0.58) | MAOBPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052442-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-09-11 | — | — | EP | disclosed |