Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 3/20 | 0.34 |
| ▸ | ATP4B | P51164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.33 |
| ▸ | BRS3 | P32247 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666063 | 0.85 | KMT2A (0.42) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL9446042 | 0.83 | KMT2A (0.38) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL13136704 | 0.82 | PKM (0.42) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL9708898 | 0.82 | WDR5 (0.42) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL9446025 | 0.82 | KMT2A (0.40) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL4958916 | 0.81 | KMT2A (0.41) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL5197626 | 0.81 | KMT2A (0.41) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL9812452 | 0.81 | KMT2A (0.41) | KMT2AWDR5AGXTPDE10AATP4A | |
| Water SCHEMBL4555319 | 0.80 | KMT2A (0.40) | KMT2AWDR5AGXTPDE10AATP4A | |
| SCHEMBL9279388 | 0.80 | KMT2A (0.40) | KMT2AWDR5AGXTPDE10AATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176308-A2 | 2-(Pyridylalkylenesulfinyl) benzimidazoles | THE UPJOHN COMPANY (US) | 1986-04-02 | — | — | EP | claimed |