SCHEMBL109622

SCHEMBL109622

C=COC(=O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HDAC1 Q13547 1/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
HIF1A Q16665 1/20 0.47
SRD5A2 P31213 1/20 0.47
TNF P01375 1/20 0.46
KLF5 Q13887 1/20 0.46
NOD1 Q9Y239 1/20 0.46
PRSS1 P07477 1/20 0.44
ACR P10323 1/20 0.44
LMNA P02545 1/20 0.44
ALOX15 P16050 1/20 0.44
APEX1 P27695 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL8097732 0.95 MAPT (0.49) MAPTTDP1L3MBTL1HDAC1CA1
Crotonic Acid SCHEMBL15350522 0.88 TNF (0.45) MAPTTDP1L3MBTL1HDAC1CA1
Crotonic Acid SCHEMBL15350519 0.88 TNF (0.45) MAPTTDP1L3MBTL1HDAC1CA1
SCHEMBL295796 0.84 ALDH1A1 (0.40) MAPTTDP1CA1CA2ALDH1A1
SCHEMBL29110210 0.83 MAPT (0.50) MAPTTDP1L3MBTL1HDAC1CA1
SCHEMBL6894972 0.83 MAPT (0.50) MAPTTDP1L3MBTL1HDAC1CA1
SCHEMBL28944014 0.82 ALDH1A1 (0.39) MAPTTDP1CA1CA2ALDH1A1
SCHEMBL28545736 0.81 CA12 (0.49) MAPTTDP1CA1CA2ALDH1A1
SCHEMBL715321 0.81 CES2 (0.53) MEN1KMT2ASRD5A2PRSS1ACR
Acetic Acid SCHEMBL27275952 0.80 TSHR (0.40) MAPTTDP1L3MBTL1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2244 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080020-A Rapamycin derivative, and preparation method and application thereof 2026-05-26 CN claimed
US-12595396-B2 Acid resistant filter media ENTEGRIS, INC. (US) 2026-04-07 US claimed
EP-3813780-B1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AT LEAST ONE COPOLYMER DERIVED FROM THE POLYMERIZATION OF AT LEAST ONE CROTONIC ACID MONOMER AND OF AT LEAST ONE VINYL ESTER MONOMER AND A FATTY AMINE OREAL (FR) 2025-12-24 EP claimed
CN-114206958-B Fluoropolymer for metal clad laminate, composition for metal clad laminate, curable composition, metal clad laminate, and printed board 大金工业株式会社 2025-06-03 CN claimed
US-12161746-B2 Aerosol hair dyeing device based on a crotonic acid copolymer and a fatty amine L'OREAL (FR) 2024-12-10 US claimed
US-11980682-B2 Composition for dyeing keratin fibres, comprising at least one copolymer derived from the polymerization of at least one crotonic acid monomer and of at least one vinyl ester monomer and a fatty amine L'OREAL (FR) 2024-05-14 US claimed
US-20230190625-A1 PROCESS FOR ALTERING THE COLOR OF KERATIN FIBERS L'OREAL (FR) 2023-06-22 US claimed
EP-4168165-A1 COMPOSITE FILTER MEDIA Entegris, Inc. (US) 2023-04-26 EP claimed
EP-4168166-A1 ACID RESISTANT FILTER MEDIA Entegris, Inc. (US) 2023-04-26 EP claimed
US-20230058827-A1 AEROSOL HAIR DYEING DEVICE BASED ON A CROTONIC ACID COPOLYMER AND A FATTY AMINE L'OREAL (FR) 2023-02-23 US claimed
US-6309585-B1 Curable casting compositions having a high refractive index and high impact resistance RODENSTOCK NORTH AMERICA, INC. 2001-10-30 US claimed
US-20010018478-A1 Curable casting compositons having a high refractive index and high impact resistance OPTISCHE WERKE G. RODENSTOCK KG (DE) 2001-08-30 US claimed
WO-2000064655-A1 HIGH INDEX CURABLE CASTING COMPOSITIONS 2C OPTICS, INC. (US) 2000-11-02 WO claimed
WO-1998042761-A1 MODIFIED RUBBER POLYMER LATEX THE UNIVERSITY OF SYDNEY (AU) 1998-10-01 WO claimed
EP-0745154-B1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM LIGNOZYM GMBH (DE) 1998-09-16 EP claimed
EP-0222157-B1 RESIN COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-12-30 EP claimed
US-4985519-A FLUOROOLEFIN, VINYL ESTER, HYDROXYL-CONTAINING ALLYL ETHER, AND CARBOXYL-CONTAINING MONOMER CENTRAL GLASS COMPANY, LIMITED (JP) 1991-01-15 US claimed
US-4886862-A MOISTURE-CURABLE SILYL-GROUP CONTAINING COPOLYMER OF A FLUOROALKYL PERVINYL ETHER AND A VINYL CARBOXYLATE, CATALYST AND SOLVENT; PAINTS; COATINGS, WEATHERPROOFING; HARDNESS DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-12-12 US claimed
US-4690968-A VINYL ESTER, VINYL ETHER, HYDROXY VINY ETHER COMONOMERS; COATINGS AND PAINTS DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-09-01 US claimed
EP-0222157-A2 Resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-05-20 EP claimed