Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.70 |
| ▸ | CA12 | O43570 | 10/20 | 0.57 |
| ▸ | CA1 | P00915 | 10/20 | 0.57 |
| ▸ | CA2 | P00918 | 10/20 | 0.57 |
| ▸ | CA9 | Q16790 | 9/20 | 0.57 |
| ▸ | CA6 | P23280 | 8/20 | 0.57 |
| ▸ | CA7 | P43166 | 8/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.57 |
| ▸ | CA3 | P07451 | 7/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.57 |
| ▸ | CA5A | P35218 | 7/20 | 0.57 |
| ▸ | JAK3 | P52333 | 2/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198982 | 0.92 | CISD1 (0.64) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL1716052 | 0.82 | CISD1 (1.00) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11874599 | 0.81 | CISD1 (0.72) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11790092 | 0.81 | CISD1 (0.70) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL12418658 | 0.80 | CISD1 (0.81) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11778816 | 0.80 | CISD1 (0.48) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11705514 | 0.79 | CISD1 (0.67) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL10962539 | 0.78 | CISD1 (0.66) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11780949 | 0.77 | CISD1 (0.46) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11841241 | 0.77 | CISD1 (0.53) | CISD1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056970-B1 | ANTHRANILIC ACIDS SUBSTITUTED BY BASIC GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |