Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 12/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA6 | P23280 | 5/20 | 0.43 |
| ▸ | CA5A | P35218 | 5/20 | 0.43 |
| ▸ | CA7 | P43166 | 5/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 4/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778816 | 0.89 | CISD1 (0.48) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11777207 | 0.86 | SIRT2 (0.39) | CISD1ALDH1A1BRAFSIRT2 | |
| Acetanilide SCHEMBL11798783 | 0.85 | CISD1 (0.49) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11777537 | 0.80 | CISD1 (0.40) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL22515417 | 0.79 | CISD1 (0.73) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11796943 | 0.78 | BRAF (0.37) | CISD1BRAF | |
| SCHEMBL10963208 | 0.77 | CISD1 (0.70) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11198982 | 0.77 | CISD1 (0.64) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11781753 | 0.76 | CISD1 (0.41) | CISD1CA12CA1CA2CA9 | |
| SCHEMBL11790756 | 0.75 | CISD1 (0.58) | CISD1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |