Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17030368 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9289576 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL6251885 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL12794189 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9572259 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13206588 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL18256420 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3322341 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL83395 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13223919 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550889-B1 | Process for producing L-Ambrox | KURARAY CO (JP) | 1996-09-18 | — | — | EP | claimed |
| US-5290955-A | Process for producing L-ambrox | KURARAY CO., LTD. (JP) | 1994-03-01 | — | — | US | claimed |
| JP-57145869-A | — | — | None | — | — | JP | disclosed |
| US-20120301956-A1 | Novel hydroxylated enantiomers of (-) 3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan as perfuming agents derived from a fungal fermentation process | RAHMAN ATTAUR (PK) | 2012-11-29 | — | — | US | disclosed |
| US-8153826-B2 | Process for production of (±)-3a,6,6,9a-Tetramethyldecahydronaphtho[2,1-b]Furan-2(1H)-one | KAO CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20090270639-A1 | PROCESS FOR PRODUCTION OF (±)-3A,6,6,9A- TETRAMETHYLDECAHYDRONAPHTHO[2,1-B]FURAN-2(1H)-ONE | KAO CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| US-7019152-B2 | Process for the optical resolution of a precursor of sclareolide | FIRMENICH SA (CH) | 2006-03-28 | — | — | US | disclosed |
| EP-1527034-B1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A PRECURSOR OF SCLAREOLIDE | FIRMENICH & CIE (CH) | 2006-01-04 | — | — | EP | disclosed |
| US-20040192960-A1 | Process for the optical resolution of a precursor of sclareolide | FIRMENICH SA (CH) | 2004-09-30 | — | — | US | disclosed |
| EP-0550889-B1 | Process for producing L-Ambrox | KURARAY CO (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5347048-A | Process for producing (±)-2,5,5,8a-tetramethyl-1-(carboxymethyl)-2-hydroxydecalin | KURARAY CO., LTD. (JP) | 1994-09-13 | — | — | US | disclosed |
| US-5290955-A | Process for producing L-ambrox | KURARAY CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5290955-A | Process for producing L-ambrox | KURARAY CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0165458-A2 | (+)-Ambrox, process for production thereof and use thereof | T. HASEGAWA COMPANY, LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |
| JP-S57145869-A | PREPARATION OF D,L-NORAMBRENOLIDE | JAPAN TOBACCO INC | 1982-09-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270639-A1 | PROCESS FOR PRODUCTION OF (±)-3A,6,6,9A- TETRAMETHYLDECAHYDRONAPHTHO[2,1-B]FURAN-2(1H)-ONE | COASY, FASN, CYP2C9 | ALDH1A1 219/4885CYP3A4 38/4885CYP2C9 3/4885 |
| US-20040192960-A1 | Process for the optical resolution of a precursor of sclareolide | LSS, CYP51A1, DHCR7 | ALDH1A1 494/4885CYP3A4 450/4885CYP2C9 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.