Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17030368 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9289576 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL6251885 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL12794189 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL1096342 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9572259 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13206588 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL18256420 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL83395 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13223919 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215619-A2 | ANTIMICROBIAL COMPOSITIONS AND USES FOR TREATMENT OF CLOSTRIDIOIDES DIFFICILE, MYCOBACTERIUM TUBERCULOSIS, AND ENTEROCOCCUS FAECALIS INFECTION | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| EP-1868964-B1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH & CIE (CH) | 2016-11-23 | — | — | EP | disclosed |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2010-11-04 | — | — | US | disclosed |
| US-7763758-B2 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2010-07-27 | — | — | US | disclosed |
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA | 2010-05-27 | — | — | US | disclosed |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2008-03-20 | — | — | US | disclosed |
| EP-0472123-B1 | Propellanes | GIVAUDAN ROURE INT (CH) | 1994-05-04 | — | — | EP | disclosed |
| EP-0472123-A1 | Propellanes | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | ADH5, ADH1A, ADH1C | ALDH1A1 1267/4885CYP3A4 107/4885CYP2C9 1104/4885 |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | ADH1C, ADH5, PHOSPHO1 | ALDH1A1 1786/4885CYP3A4 1397/4885CYP2C9 1974/4885 |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | ADH5, ADH1A, ADH1C | ALDH1A1 1267/4885CYP3A4 107/4885CYP2C9 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.