Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 5/20 | 0.35 |
| ▸ | CASR | P41180 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096485 | 0.82 | KDM1A (0.39) | CCR5KDM1ARORCTACR1 | |
| SCHEMBL1095794 | 0.81 | CASR (0.45) | KDM1ACASR | |
| SCHEMBL3570514 | 0.75 | KDM1A (0.53) | CCR5KDM1ARORCTACR1 | |
| SCHEMBL4076516 | 0.75 | CCR5 (0.41) | CCR5KDM1AESR1ESR2RORC | |
| SCHEMBL1096488 | 0.75 | CCR5 (0.39) | CCR5KDM1AESR1ESR2RORC | |
| SCHEMBL1096982 | 0.74 | CASR (0.41) | CASR | |
| SCHEMBL1095736 | 0.74 | CASR (0.45) | KDM1ACASR | |
| Hydrochloric Acid SCHEMBL1096824 | 0.73 | CASR (0.45) | KDM1ACASR | |
| SCHEMBL4107034 | 0.73 | CASR (0.47) | CCR5RORCCASR | |
| SCHEMBL4093845 | 0.73 | CASR (0.47) | CCR5RORCCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153658-B2 | Piperidine derivative or salt thereof | ASTELLAS PHARMA, INC. (JP) | 2012-04-10 | — | — | US | disclosed |