Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170803 | 0.84 | KDM4E (0.48) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL10961560 | 0.84 | KDM4E (0.48) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL11155201 | 0.82 | TSHR (0.49) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL11154814 | 0.81 | KMT2A (0.45) | KDM4EALDH1A1TSHRHPGDGAA | |
| SCHEMBL10964934 | 0.80 | ALDH1A1 (0.49) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL11160089 | 0.79 | KMT2A (0.46) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| Water SCHEMBL10964357 | 0.78 | KMT2A (0.45) | HSD17B10ALDH1A1HPGDGAAMAPT | |
| SCHEMBL11158593 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL11163717 | 0.75 | MAPT (0.61) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| Lithium Ion SCHEMBL11164273 | 0.75 | KDM4E (0.46) | HSD17B10KDM4EALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400508-A | AGRICULTURE; PLANT DISEASES; ANTISEPTICS | UBE INDUSTRIES, LTD. (JP) | 1983-08-23 | — | — | US | claimed |
| EP-0052341-A1 | Orotic acid derivatives and their use as agricultural chemicals | UBE INDUSTRIES, LTD. (JP) | 1982-05-26 | — | — | EP | claimed |
| EP-0052341-B1 | OROTIC ACID DERIVATIVES AND THEIR USE AS AGRICULTURAL CHEMICALS | UBE INDUSTRIES, LTD. (JP) | 1985-05-29 | — | — | EP | disclosed |
| US-4400508-A | AGRICULTURE; PLANT DISEASES; ANTISEPTICS | UBE INDUSTRIES, LTD. (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0052341-A1 | Orotic acid derivatives and their use as agricultural chemicals | UBE INDUSTRIES, LTD. (JP) | 1982-05-26 | — | — | EP | disclosed |