Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13936399 | 0.85 | KMT2A (0.73) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL29655205 | 0.83 | KMT2A (0.71) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL10165944 | 0.83 | KMT2A (0.71) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL12811737 | 0.83 | KMT2A (0.71) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL5442803 | 0.83 | KMT2A (0.71) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL1640485 | 0.83 | KMT2A (0.71) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL4341926 | 0.83 | KMT2A (0.71) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL6242064 | 0.82 | TSHR (0.80) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL11363904 | 0.82 | KMT2A (0.65) | KMT2AKDM4EPOLBATMHSD17B10 | |
| SCHEMBL10502377 | 0.81 | KMT2A (1.00) | KMT2AKDM4EPOLBATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |