SCHEMBL29655205

SCHEMBL29655205

COC(=O)c1ccccc1NC(C)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.71
LMNA P02545 3/20 0.71
KDM4E B2RXH2 6/20 0.67
POLB P06746 2/20 0.67
ATM Q13315 1/20 0.67
HSD17B10 Q99714 6/20 0.64
ALDH1A1 P00352 6/20 0.64
TSHR P16473 5/20 0.63
GAA P10253 2/20 0.63
MAPT P10636 2/20 0.63
MAPK1 P28482 2/20 0.63
CYP2C19 P33261 2/20 0.62
HPGD P15428 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
HTT P42858 1/20 0.61
ALOX15 P16050 1/20 0.61
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
ALOX12 P18054 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1640485 1.00 KMT2A (0.71) KMT2ALMNAKDM4EPOLBATM
SCHEMBL15114720 0.87 KDM4E (0.66) KMT2ALMNAKDM4EPOLBATM
SCHEMBL13936399 0.86 KMT2A (0.73) KMT2ALMNAKDM4EPOLBATM
SCHEMBL28600269 0.85 KDM4E (0.62) KMT2ALMNAKDM4EPOLBATM
SCHEMBL5442803 0.85 KMT2A (0.71) KMT2ALMNAKDM4EPOLBATM
SCHEMBL10165944 0.85 KMT2A (0.71) KMT2ALMNAKDM4EPOLBATM
SCHEMBL4341926 0.85 KMT2A (0.71) KMT2ALMNAKDM4EPOLBATM
SCHEMBL12811737 0.85 KMT2A (0.71) KMT2ALMNAKDM4EPOLBATM
SCHEMBL18737813 0.84 SMN1; SMN2 (0.63) KMT2ALMNAKDM4EPOLBATM
SCHEMBL7426825 0.84 HSD17B10 (0.63) KMT2ALMNAKDM4EPOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO claimed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US claimed
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO disclosed
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO disclosed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US disclosed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 KMT2A 2697/4885LMNA 4834/4885KDM4E 3699/4885
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF L3MBTL4, L3MBTL3, L3MBTL1 KMT2A 404/4885LMNA 2740/4885KDM4E 276/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 KMT2A 2697/4885LMNA 4834/4885KDM4E 3699/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 KMT2A 2697/4885LMNA 4834/4885KDM4E 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.