Ether

Ether

SCHEMBL10965740

CCOCC.O=C(OCC1CO1)c1ccccc1O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
BCHE P06276 3/20 0.46
KMT2A Q03164 2/20 0.45
TSHR P16473 2/20 0.45
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MAPK1 P28482 1/20 0.43
SIRT5 Q9NXA8 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL709268 0.92 TSHR (0.54) DHFRTDP1TSHRL3MBTL1MAPK1
SCHEMBL15164276 0.92 TDP1 (0.56) DHFRTDP1BCHEKMT2ATSHR
SCHEMBL5038684 0.90 TDP1 (0.51) DHFRTDP1BCHEKMT2ATSHR
Glycidol SCHEMBL5038682 0.86 TDP1 (0.50) DHFRTDP1BCHEKMT2ATSHR
SCHEMBL23237784 0.85 TSHR (0.50) DHFRTDP1TSHRL3MBTL1MAPK1
SCHEMBL29374975 0.82 DHFR (0.59) DHFRTDP1TSHRL3MBTL1MAPK1
SCHEMBL21801767 0.82 DHFR (0.59) DHFRTDP1TSHRL3MBTL1MAPK1
SCHEMBL121520 0.82 DHFR (0.59) DHFRTDP1TSHRL3MBTL1MAPK1
Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL283022 0.82 NPC1 (0.52) KMT2ATSHRLMNANPC1RAB9A
SCHEMBL28387457 0.81 DHFR (0.55) DHFRTDP1TSHRL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038635-B1 RESIN COMPOSITION FOR POWDER COATING DAINIPPON INK AND CHEMICALS, INC. (JP) 1985-03-20 EP disclosed
US-4499239-A CURABLE BLEND OF POLYESTER AND GLYCIDYL-CONTAINING ACRYLIC POLYMER; SMOOTHNESS; WEATHERPROOFING DAINIPPON INK AND CHEMICALS, INC. (JP) 1985-02-12 US disclosed
EP-0038635-A1 Resin composition for powder coating DAINIPPON INK AND CHEMICALS, INC. (JP) 1981-10-28 EP disclosed