SCHEMBL10965748

SCHEMBL10965748

[CH2]CCCOc1nc(OCC2CO2)nc(OCC2CO2)n1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 6/20 0.40
TSHR P16473 4/20 0.40
TP53 P04637 3/20 0.40
HIF1A Q16665 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP3A4 P08684 1/20 0.40
GLA P06280 1/20 0.38
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PKM P14618 2/20 0.36
CYP1A2 P05177 1/20 0.36
PPARG P37231 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
FGFR1 P11362 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397562 0.83 TDP1 (0.48) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL487480 0.83 TDP1 (0.48) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL29398866 0.83 TDP1 (0.48) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL10963909 0.80 TSHR (0.42) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL49542 0.76 SMN1; SMN2 (0.47) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL3677603 0.76 TDP1 (0.42) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL15005092 0.76 ALDH1A1 (0.39) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL27489779 0.76 TDP1 (0.47) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL11213546 0.74 ALDH1A1 (0.42) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL22493953 0.74 TSHR (0.54) TDP1ALDH1A1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP claimed
US-4498957-A Aromatic polyamide paper-like sheet and processes for producing the same TEIJIN LIMITED (JP) 1985-02-12 US disclosed
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP disclosed