SCHEMBL49542

SCHEMBL49542

CCCCOc1nc(Cl)nc(OCC2CO2)n1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 7/20 0.41
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 4/20 0.38
TP53 P04637 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
HIF1A Q16665 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP1A2 P05177 1/20 0.38
PPARG P37231 1/20 0.38
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.35
PKM P14618 2/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
TLR7 Q9NYK1 7/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48796 0.86 TDP1 (0.41) SMN1; SMN2ALDH1A1TDP1TSHRTP53
SCHEMBL4308247 0.82 TDP1 (0.41) SMN1; SMN2ALDH1A1TDP1TSHRTP53
SCHEMBL6051629 0.82 RAB9A (0.41) SMN1; SMN2HPGDCYP1A2CYP3A4LMNA
SCHEMBL27448078 0.82 SMN1; SMN2 (0.52) SMN1; SMN2ALDH1A1TDP1TSHRMEN1
SCHEMBL9174762 0.81 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1TDP1TSHRTP53
SCHEMBL1318906 0.79 RAB9A (0.41) SMN1; SMN2ALDH1A1TSHRHPGDCYP1A2
SCHEMBL29398866 0.77 TDP1 (0.48) SMN1; SMN2ALDH1A1TDP1TSHRTP53
SCHEMBL487480 0.77 TDP1 (0.48) SMN1; SMN2ALDH1A1TDP1TSHRTP53
SCHEMBL29397562 0.77 TDP1 (0.48) SMN1; SMN2ALDH1A1TDP1TSHRTP53
SCHEMBL10965748 0.76 TDP1 (0.41) SMN1; SMN2ALDH1A1TDP1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0550210-B1 Polyphenylene ether/polyamide compositions GEN ELECTRIC (US) 1997-03-19 EP claimed
EP-0550206-A2 Polyphenylene ether/polyamide compositions GENERAL ELECTRIC COMPANY (US) 1993-07-07 EP claimed
EP-0550210-A1 Polyphenylene ether/polyamide compositions GENERAL ELECTRIC COMPANY (US) 1993-07-07 EP claimed
US-8133844-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-8129311-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8124563-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-7981837-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-7968496-B2 Heat-sensitive transfer image-receiving sheet, image forming method using heat-sensitive transfer system and method of producing heat-sensitive transfer image receiving sheet FUJIFILM CORPORATION (JP) 2011-06-28 US disclosed
US-7968495-B2 Heat-sensitive transfer image-receiving sheet and producing method thereof FUJIFILM CORPORATION (JP) 2011-06-28 US disclosed
US-7932210-B2 Image-forming method using thermal transfer system FUJIFILM CORPORATION (JP) 2011-04-26 US disclosed
US-7906267-B2 mulilayer, support, latex receivers with different elastic modulus and heat insulating polymer containing hollow particles FUJIFILM CORPORATION (JP) 2011-03-15 US disclosed
US-5010144-A Copolymerized with polyesters, polyamides and polyolefns contining nulceophilic groups; impact strength GENERAL ELECTRIC COMPANY (US) 1991-04-23 US disclosed
US-4980415-A Compositions comprising polyphenylene ethers and reactive graft polymers GENERAL ELECTRIC COMPANY (US) 1990-12-25 US disclosed
EP-0395993-A2 Compositions comprising polyphenylene ethers and reactive graft polymers GENERAL ELECTRIC COMPANY (US) 1990-11-07 EP disclosed
EP-0374517-A2 Polyphenylene ether-polyamide copolymers from epoxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1990-06-27 EP disclosed
US-4895945-A Epoxidized chlorotriazine compounds GENERAL ELECTRIC COMPANY (US) 1990-01-23 US disclosed
EP-0349717-A2 Polyphenylene ether-polyester copolymers from epoxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1990-01-10 EP disclosed
EP-0347828-A2 Compositions comprising polyphenylene ether-polyester copolymers from epoxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1989-12-27 EP disclosed
EP-0347827-A2 Epoxytriazine-capped polyphenylene ethers and method of preparation GENERAL ELECTRIC COMPANY (US) 1989-12-27 EP disclosed
EP-0347539-A2 Epoxytriazine-capped polyphenylene ethers and method for their preparation GENERAL ELECTRIC COMPANY (US) 1989-12-27 EP disclosed