Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617963 | 1.00 | AHR (0.56) | AHRKEAP1PDPK1BACE1BCHE | |
| SCHEMBL29876050 | 0.98 | AHR (0.54) | AHRKEAP1PDPK1BACE1BCHE | |
| Sulfuric Acid SCHEMBL23540701 | 0.90 | KEAP1 (0.50) | AHRKEAP1PDPK1BACE1BCHE | |
| Acetic Acid SCHEMBL23646036 | 0.88 | KEAP1 (0.58) | AHRKEAP1PDPK1BACE1BCHE | |
| SCHEMBL9119040 | 0.79 | G6PD (0.65) | AHRKEAP1PDPK1BACE1BCHE | |
| Benzimidazole SCHEMBL3536974 | 0.79 | QPCT (0.44) | AHRKEAP1PDPK1CA1CA2 | |
| SCHEMBL31492457 | 0.75 | AHR (0.60) | AHRKEAP1PDPK1BACE1BCHE | |
| SCHEMBL16719974 | 0.73 | AHR (0.40) | AHRKEAP1PDPK1BACE1BCHE | |
| SCHEMBL3334473 | 0.73 | AHR (0.58) | AHRKEAP1PDPK1BACE1BCHE | |
| SCHEMBL3876150 | 0.71 | AHR (0.56) | AHRKEAP1PDPK1BACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4400 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622856-B2 | Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer | HENKEL AG & CO. KGAA (DE) | 2026-05-12 | — | — | US | claimed |
| US-12350265-B2 | Pharmaceutical composition for treating acute myeloid leukemia, containing FLT3 inhibitor and chemotherapeutic agents | HANMI PHARM. CO., LTD. (KR) | 2025-07-08 | — | — | US | claimed |
| US-12344708-B2 | Tissue-adhesive hydrogels | POLYGANICS IP B.V. (NL) | 2025-07-01 | — | — | US | claimed |
| WO-2025137591-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR PROMOTING ZINC SOLUBILIZATION AND ZINC UPTAKE IN PLANTS | Tenfold Technologies, LLC (US) | 2025-06-26 | — | — | WO | claimed |
| WO-2025061319-A2 | IMPROVING THE WASHING FASTNESS OF LEVEL 2 COLORATIONS BY MEANS OF A SEALING PROCESS USING SILANES | HENKEL AG & CO. KGAA (DE) | 2025-03-27 | — | — | WO | claimed |
| EP-4496556-A1 | AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, AT LEAST ONE OXIDATION DYE PRECURSOR OF THE COUPLER TYPE AND ISATIN | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | claimed |
| EP-4496557-A1 | MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED COMPLEXING AGENT | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | claimed |
| EP-4496558-A1 | MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED ALKALISING AGENT | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | claimed |
| EP-4496555-A1 | MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE P-PHENYLENEDIAMINE TYPE, ISATIN AND AT LEAST ONE OXIDISING AGENT | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | claimed |
| EP-4496559-A1 | AGENT FOR OXIDATIVE DYEING OF KERATIN FIBRES, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | claimed |
| EP-0200583-B1 | 7-HYDROXY INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, USE AS MEDICINE, COMPOUNDS CONTAINING THEM AND THEIR INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | claimed |
| EP-0415802-A1 | Keratinous fibres dyeing process with monohydroxyindole and hydroxyindole-5,6-disubstituted and composition | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |
| EP-0379409-A1 | Products based on polymer particles containing melanine pigments, process for their preparation, and their use, particularly cosmetically | L'OREAL (FR) | 1990-07-25 | — | — | EP | claimed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | claimed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | claimed |
| WO-1990001919-A1 | POLYMERIC SKIN COLORANT | THE GILLETTE COMPANY (US) | 1990-03-08 | — | — | WO | claimed |
| US-4776857-A | HYDROXYINDOLES AND PERIODATE OXIDIZERS; HAIR AND SKIN | REPLIGEN CORPORATION (US) | 1988-10-11 | — | — | US | claimed |
| EP-0271186-A1 | Hydroxyindoles and their use in dyeing | REPLIGEN CORPORATION (US) | 1988-06-15 | — | — | EP | claimed |
| US-4694011-A | CARDIOVASCULAR DISORDERS | ROUSSEL UCLAF (FR) | 1987-09-15 | — | — | US | claimed |
| EP-0200583-A1 | 7-Hydroxy indole derivatives, process for their preparation, use as medicine, compounds containing them and their intermediates | ROUSSEL-UCLAF (FR) | 1986-11-05 | — | — | EP | claimed |