Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168715 | 0.93 | HTR3A (0.81) | HTR3A | |
| SCHEMBL7341277 | 0.86 | HTR3A (0.75) | HTR3A | |
| SCHEMBL15963055 | 0.84 | HTR3A (0.65) | HTR3A | |
| Lerisetron SCHEMBL141124 | 0.83 | HTR3A (1.00) | HTR3A | |
| Lerisetron SCHEMBL30669539 | 0.83 | HTR3A (1.00) | HTR3A | |
| SCHEMBL2641012 | 0.83 | CFTR (0.56) | HTR3A | |
| SCHEMBL4435849 | 0.83 | HTR3A (0.67) | HTR3A | |
| SCHEMBL14198327 | 0.82 | HTR3A (0.71) | HTR3A | |
| Lerisetron SCHEMBL29040939 | 0.82 | HTR3A (0.97) | HTR3A | |
| SCHEMBL9761998 | 0.82 | KDM4E (0.53) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079545-A1 | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1983-05-25 | — | — | EP | claimed |
| EP-0079545-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KANEBO, LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |
| US-4434265-A | STABILIZERS AGAINST OXIDATION OF OLEFIN POLYMERS | THE B.F. GOODRICH COMPANY (US) | 1984-02-28 | — | — | US | disclosed |
| US-4430343-A | ANTIHISTAMINES | KANEBO, LTD. (JP) | 1984-02-07 | — | — | US | disclosed |
| EP-0079545-A1 | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1983-05-25 | — | — | EP | disclosed |