Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762192 | 0.95 | KDM4E (0.49) | KDM4EALDH1A1TSHRHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9761957 | 0.94 | KDM4E (0.48) | KDM4EALDH1A1TSHRHTTHSD17B10 | |
| Fumaric Acid SCHEMBL9761131 | 0.91 | LMNA (0.50) | KDM4EALDH1A1TSHRHTTHSD17B10 | |
| Fumaric Acid SCHEMBL9761122 | 0.91 | LMNA (0.50) | KDM4EALDH1A1TSHRHTTHSD17B10 | |
| SCHEMBL9761943 | 0.89 | CYP2D6 (0.54) | ALDH1A1TSHRHSD17B10LMNAHTR3A | |
| SCHEMBL12354273 | 0.83 | HTR3E (0.56) | KDM4EALDH1A1TSHRHTTHSD17B10 | |
| SCHEMBL10967129 | 0.82 | HTR3A (0.71) | HTR3A | |
| SCHEMBL9760764 | 0.81 | HTR3A (0.63) | HTR3A | |
| Hydrochloric Acid SCHEMBL9762241 | 0.80 | HTR3A (0.62) | HTR3A | |
| SCHEMBL2244026 | 0.80 | HTR3E (0.61) | KDM4EALDH1A1HSD17B10LMNAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023256-A | Antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-06-11 | — | — | US | disclosed |