Clofibric Acid

Clofibric Acid

SCHEMBL147972

CC(C)(Oc1ccc(Cl)cc1)C(=O)O.CC(COc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 15/20 0.68
CYP1A2 P05177 3/20 0.68
CYP3A4 P08684 3/20 0.68
MEN1 O00255 2/20 0.68
MAPT P10636 2/20 0.68
CYP2C19 P33261 2/20 0.68
KMT2A Q03164 2/20 0.68
CYP2D6 P10635 1/20 0.68
PPARG P37231 10/20 0.59
FABP2 P12104 2/20 0.59
SLC22A12 Q96S37 1/20 0.59
PPARD Q03181 4/20 0.55
PSEN1 P49768 3/20 0.50
PSEN2 P49810 3/20 0.50
APH1B Q8WW43 3/20 0.50
NCSTN Q92542 3/20 0.50
APH1A Q96BI3 3/20 0.50
PSENEN Q9NZ42 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1305299 0.87 PPARA (0.58) PPARACYP1A2MEN1KMT2APPARG
SCHEMBL28619870 0.87 PPARA (0.58) PPARACYP1A2MEN1KMT2APPARG
SCHEMBL21895800 0.87 PPARA (0.58) PPARACYP1A2MEN1KMT2APPARG
Water SCHEMBL11798405 0.85 PPARA (0.56) PPARACYP1A2MEN1KMT2APPARG
SCHEMBL11536518 0.83 PPARA (0.54) PPARACYP1A2MEN1KMT2APPARG
Pivalate SCHEMBL10967155 0.83 PPARA (0.55) PPARACYP1A2CYP3A4MEN1MAPT
Clofibric Acid SCHEMBL102826 0.82 PPARA (1.00) PPARACYP1A2CYP3A4MEN1MAPT
Clofibric Acid SCHEMBL2227936 0.82 PPARA (1.00) PPARACYP1A2CYP3A4MEN1MAPT
Clofibric Acid SCHEMBL317991 0.81 PPARA (0.96) PPARACYP1A2CYP3A4MEN1MAPT
Clofibric Acid SCHEMBL10634899 0.81 PPARA (0.96) PPARACYP1A2CYP3A4MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120060243-A1 Herbicide-Resistant AHAS-Mutants and Methods of Use BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2012-03-08 US disclosed
EP-2385756-A1 SOYBEAN EVENT 127 AND METHODS RELATED THERETO BASF Agrochemical Products, B.V. (NL) 2011-11-16 EP disclosed
US-8041483-B2 Exterior airbag deployment techniques AUTOMOTIVE TECHNOLOGIES INTERNATIONAL, INC. (US) 2011-10-18 US disclosed
EP-2342331-A2 HERBICIDE-RESISTANT AHAS-MUTANTS AND METHODS OF USE BASF Agrochemical Products, B.V. (NL) 2011-07-13 EP disclosed