Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614321 | 0.83 | MAPT (0.45) | ALDH1A1TSHRPOLBKDM4EHPGD | |
| SCHEMBL5094461 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2ARXFP1HSD17B10 | |
| SCHEMBL645556 | 0.79 | LMNA (0.42) | ALDH1A1TSHRKDM4EHPGDRXFP1 | |
| SCHEMBL16334438 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRPOLBKDM4EHPGD | |
| SCHEMBL14346648 | 0.79 | TSHR (0.59) | ALDH1A1TSHRHPGDHSD17B10CYP1A2 | |
| SCHEMBL995726 | 0.76 | HPGD (0.46) | ALDH1A1HPGDKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL23130991 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRPOLBKDM4EHPGD | |
| SCHEMBL7896753 | 0.71 | EPHX1 (0.67) | ALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL9360194 | 0.70 | EPHX1 (0.49) | ALDH1A1TSHRPOLBKDM4EHPGD | |
| SCHEMBL31426653 | 0.70 | ALDH1A1 (0.43) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075117-B1 | 2H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1985-03-13 | — | — | EP | disclosed |
| US-4428766-A | 2N-1,2,4,6,Thiatriazine-1,1-dioxides and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0075117-A2 | 2H-1,2,4,6-thiatriazine-1,1-dioxides, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |
| US-4343648-A | 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-10 | — | — | US | disclosed |