Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394776 | 0.97 | TAAR1 (0.37) | TAAR1POLBPNMTCYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL28656395 | 0.95 | TAAR1 (0.35) | TAAR1POLBPNMTCYP1A2CYP2A6 | |
| Water SCHEMBL4649643 | 0.95 | TAAR1 (0.35) | TAAR1POLBPNMTCYP1A2CYP2A6 | |
| SCHEMBL4729834 | 0.87 | PNMT (0.38) | TAAR1PNMTCYP1A2CYP2A6TSHR | |
| SCHEMBL8213267 | 0.85 | TAAR1 (0.31) | TAAR1PNMT | |
| SCHEMBL11021619 | 0.78 | TAAR1 (0.34) | TAAR1POLBPNMT | |
| SCHEMBL10946904 | 0.78 | POLB (0.52) | TAAR1POLBCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL3667007 | 0.78 | TAAR1 (0.34) | TAAR1POLBPNMT | |
| SCHEMBL16099683 | 0.78 | TAAR1 (0.54) | TAAR1CYP1A2CYP2A6 | |
| SCHEMBL1976464 | 0.77 | POLB (0.39) | TAAR1POLBPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113363390-A | High-efficiency perovskite solar cell and preparation method | 南开大学 | 2021-09-07 | — | — | CN | disclosed |
| EP-0049049-B1 | 5-AMINO-TETRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1985-11-13 | — | — | EP | disclosed |