Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626883 | 0.82 | CA12 (0.63) | TP53ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11030758 | 0.82 | CYP1A2 (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL21847252 | 0.79 | ALDH1A1 (0.62) | TP53ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10968014 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL2782599 | 0.78 | HSD17B10 (0.50) | TP53ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14584391 | 0.78 | SMN1; SMN2 (0.57) | TP53ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10966745 | 0.78 | HPGD (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL10477897 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL549173 | 0.75 | KMT2A (0.63) | TP53ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8481546 | 0.75 | KIF11 (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |