Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168415 | 1.00 | PKM (0.40) | PKMDGAT1TSHRHSD17B10 | |
| SCHEMBL24471392 | 0.80 | PKM (0.40) | PKMDGAT1 | |
| SCHEMBL15827293 | 0.75 | TSHR (0.36) | DGAT1TSHRHSD17B10 | |
| SCHEMBL10355716 | 0.72 | PKM (0.41) | PKMDGAT1 | |
| SCHEMBL11322351 | 0.71 | TSHR (0.45) | TSHR | |
| SCHEMBL2871889 | 0.71 | TSHR (0.43) | DGAT1TSHRHSD17B10 | |
| SCHEMBL11328322 | 0.71 | TSHR (0.45) | TSHR | |
| SCHEMBL11320019 | 0.70 | EPHX2 (0.38) | TSHRHSD17B10 | |
| SCHEMBL11320026 | 0.70 | EPHX2 (0.38) | TSHRHSD17B10 | |
| SCHEMBL27500342 | 0.70 | ESR1 (0.44) | TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045281-B1 | TRIAZOLINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1985-05-08 | — | — | EP | disclosed |
| US-4406905-A | COMPLEXING, ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1983-09-27 | — | — | US | disclosed |
| EP-0045281-A1 | Triazoline derivatives and processes for their preparation | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | disclosed |