Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304012 | 0.80 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL18610328 | 0.80 | DGAT1 (0.37) | TSHRDGAT1 | |
| SCHEMBL19749962 | 0.80 | DGAT1 (0.37) | TSHRDGAT1 | |
| SCHEMBL12180891 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL1316301 | 0.77 | — | — | |
| SCHEMBL15195523 | 0.77 | — | — | |
| SCHEMBL1316303 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL1314833 | 0.77 | KDM4E (0.39) | DGAT1 | |
| SCHEMBL11168415 | 0.75 | PKM (0.40) | TSHRHSD17B10DGAT1 | |
| SCHEMBL10967310 | 0.75 | PKM (0.40) | TSHRHSD17B10DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759512-B2 | Methods of preparation of macrocyclic compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-06-24 | — | — | US | disclosed |