Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109791 | 0.86 | EGFR (0.53) | EGFRERBB2KMT2AERBB4KDR | |
| SCHEMBL10969276 | 0.84 | KDM4E (0.57) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10967972 | 0.84 | RAB9A (0.59) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10971593 | 0.82 | EGFR (0.52) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10970783 | 0.82 | CYP1A2 (0.51) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10970750 | 0.80 | EGFR (0.51) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10972874 | 0.80 | CYP1A2 (0.49) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10966973 | 0.79 | EGFR (0.50) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10967368 | 0.79 | KDM4E (0.53) | EGFRERBB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL10972059 | 0.78 | EGFR (0.50) | EGFRERBB2MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543356-A | Quinazoline derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-24 | — | — | US | disclosed |