Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095190 | 0.84 | RPS6KB1 (0.43) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10967972 | 0.83 | RAB9A (0.59) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10716653 | 0.77 | MAPT (1.00) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10966662 | 0.76 | KMT2A (0.55) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10969276 | 0.76 | KDM4E (0.57) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL11610004 | 0.76 | MAPT (0.65) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10863521 | 0.75 | CYP3A4 (0.71) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10970783 | 0.74 | CYP1A2 (0.51) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10971593 | 0.74 | EGFR (0.52) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 | |
| SCHEMBL11608951 | 0.74 | MAPT (0.56) | MAPTCYP3A4CYP2D6MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543356-A | Quinazoline derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-24 | — | — | US | disclosed |