Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.65 |
| ▸ | CTSA | P10619 | 2/20 | 0.61 |
| ▸ | SCNN1A | P37088 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967688 | 1.00 | FTO (0.65) | FTOCTSASCNN1AALDH1A1KDM4E | |
| SCHEMBL10966140 | 0.81 | CTSA (0.53) | FTOCTSASCNN1AALDH1A1KDM4E | |
| SCHEMBL10966156 | 0.81 | CTSA (0.53) | FTOCTSASCNN1AALDH1A1KDM4E | |
| SCHEMBL523475 | 0.79 | FTO (1.00) | FTOL3MBTL1MMEPYGL | |
| SCHEMBL523354 | 0.79 | FTO (1.00) | FTOL3MBTL1MMEPYGL | |
| SCHEMBL29619835 | 0.79 | FTO (1.00) | FTOL3MBTL1MMEPYGL | |
| SCHEMBL523353 | 0.79 | FTO (1.00) | FTOL3MBTL1MMEPYGL | |
| SCHEMBL1428415 | 0.79 | SCNN1A (0.55) | FTOCTSASCNN1AALDH1A1KDM4E | |
| SCHEMBL18748447 | 0.77 | SCNN1A (0.53) | FTOCTSASCNN1AALDH1A1KDM4E | |
| SCHEMBL17108573 | 0.77 | SCNN1A (0.53) | FTOCTSASCNN1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057572-B1 | ALKANOLAMINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-31 | — | — | EP | disclosed |
| US-4399138-A | DIURETICS, ADRENERGIC BLOCKING AND HYPOTENSIVE AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-16 | — | — | US | disclosed |
| EP-0057572-A1 | Alkanolamine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-11 | — | — | EP | disclosed |