Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | THPO | P40225 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18748442 | 0.86 | SCNN1A (0.53) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17108573 | 0.86 | SCNN1A (0.53) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18748447 | 0.86 | SCNN1A (0.53) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11959313 | 0.84 | SCNN1A (0.51) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18760196 | 0.84 | SCNN1A (0.51) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| Iodide SCHEMBL1428436 | 0.83 | SCNN1A (0.50) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18748444 | 0.82 | SCNN1A (0.49) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18748443 | 0.80 | PLAU (0.48) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1134633 | 0.80 | SCNN1A (0.43) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1134504 | 0.79 | SCNN1A (0.46) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201625-A1 | Organic Comopunds | NOVARTIS AG (CH) | 2011-08-18 | — | — | US | disclosed |
| EP-2300010-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2011-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201625-A1 | Organic Comopunds | OR10J3, CFTR, CLIC1 | SCNN1A 52/4885ALDH1A1 2244/4885KDM4E 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.