Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560842 | 0.86 | PTGS1 (0.50) | MT-CO2MAOBPTGS2PTGS1APP | |
| SCHEMBL13176797 | 0.84 | MT-CO2 (0.59) | MT-CO2PTGS2PTGS1CYP2C19CYP3A4 | |
| SCHEMBL19392984 | 0.83 | MT-CO2 (0.55) | MT-CO2MAOBPTGS2PTGS1APP | |
| SCHEMBL8321208 | 0.82 | MT-CO2 (0.47) | MT-CO2MAOBPTGS2PTGS1APP | |
| SCHEMBL30192791 | 0.82 | MT-CO2 (0.47) | MT-CO2MAOBPTGS2PTGS1APP | |
| SCHEMBL24875457 | 0.82 | MT-CO2 (0.47) | MT-CO2MAOBPTGS2PTGS1APP | |
| SCHEMBL13194589 | 0.82 | MT-CO2 (0.47) | MT-CO2MAOBPTGS2PTGS1APP | |
| SCHEMBL10911105 | 0.82 | FOLH1 (0.49) | MT-CO2FOLH1MAOBSHBG | |
| SCHEMBL8476208 | 0.82 | MT-CO2 (0.47) | MT-CO2MAOBPTGS2PTGS1APP | |
| SCHEMBL15563590 | 0.81 | MAOB (0.52) | MT-CO2MAOBPTGS2PTGS1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074170-B1 | CHROMAN COMPOUNDS, PROCESS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1985-10-16 | — | — | EP | disclosed |
| US-4545993-A | ANTINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| EP-0074170-A1 | Chroman compounds, process for producing them and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1983-03-16 | — | — | EP | disclosed |