Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.81 |
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.81 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.81 |
| ▸ | GMNN | O75496 | 1/20 | 0.80 |
| ▸ | APEX1 | P27695 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709094 | 1.00 | LMNA (0.81) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| SCHEMBL11814972 | 0.92 | LMNA (0.68) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| SCHEMBL4759572 | 0.91 | LMNA (0.80) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| SCHEMBL9540521 | 0.91 | LMNA (0.80) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| SCHEMBL11821921 | 0.90 | LMNA (0.70) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| SCHEMBL11445737 | 0.90 | LMNA (0.69) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| Pirenzepine SCHEMBL41705 | 0.90 | LMNA (1.00) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5501944 | 0.90 | LMNA (0.80) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| SCHEMBL10968093 | 0.90 | LMNA (0.69) | LMNACHRM2CHRM1USP2ALDH1A1 | |
| Pirenzepine SCHEMBL9254860 | 0.90 | LMNA (1.00) | LMNACHRM2CHRM1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556653-A | ANTISECRETORY, ANTIULCER AND ANTISPASMODIC AGENTS | DOMPE' FARMACEUTICA S.P.A. (IT) | 1985-12-03 | — | — | US | disclosed |
| EP-0125607-A2 | Pyrido(1,5)benzodiazepinone derivatives and pharmacological activities thereof | DOMPE' FARMACEUTICI S.p.A. (IT) | 1984-11-21 | — | — | EP | disclosed |