Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972119 | 0.92 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10972533 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11088505 | 0.87 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10972218 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10814468 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10914023 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10459499 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10459906 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10675824 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10382723 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044807-B1 | N-PHENYLSULFONYL-N'-PYRIMIDINYL- AND -TRIAZINYL UREAS | CIBA-GEIGY AG (CH) | 1985-11-21 | — | — | EP | claimed |
| US-4443245-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1984-04-17 | — | — | US | claimed |
| US-4443245-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |