Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 10/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28581963 | 0.84 | PTGER4 (0.51) | PTGER4PTGER3PTGER2 | |
| SCHEMBL28581962 | 0.84 | PTGER4 (0.51) | PTGER4PTGER3PTGER2 | |
| SCHEMBL10971336 | 0.84 | PTGER4 (0.51) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11159884 | 0.84 | PTGER4 (0.37) | PTGER4PTGER3PTGER2 | |
| SCHEMBL19513853 | 0.79 | PTGER4 (0.54) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11992514 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL14513322 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL10970283 | 0.77 | PTGER4 (0.62) | PTGER4PTGER3PTGER2 | |
| SCHEMBL18831938 | 0.77 | PTGER4 (0.62) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2576673 | 0.76 | P2RX7 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046082-B1 | 8-AZA-16,16-DIFLUOROPROSTANOIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-05 | — | — | EP | disclosed |
| US-4399290-A | ANTIULCER, ANTINFLAMMATORY AND BRONCHODILATOR AGENTS; 8-HZA PROSTANOIDS; PROSTAGLANDINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0048611-A2 | Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl)heptanoates and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-31 | — | — | EP | disclosed |
| US-4321201-A | FROM AMINE SALTS THEROF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| EP-0046082-A2 | 8-Aza-16,16-difluoroprostanoids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-17 | — | — | EP | disclosed |