Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969570 | 0.85 | TSHR (0.41) | PDE2ATSHR | |
| SCHEMBL10976215 | 0.77 | TSHR (0.58) | PDE2ATSHR | |
| SCHEMBL10969987 | 0.75 | TSHR (0.40) | TSHR | |
| SCHEMBL9576388 | 0.75 | TSHR (0.48) | PDE2ATSHR | |
| SCHEMBL10972762 | 0.74 | TSHR (0.60) | PDE2ATSHR | |
| SCHEMBL28247950 | 0.73 | CES2 (0.46) | — | |
| SCHEMBL10969460 | 0.72 | TSHR (0.41) | TSHR | |
| SCHEMBL17696924 | 0.70 | TSHR (0.43) | TSHR | |
| SCHEMBL3315570 | 0.68 | PDE2A (0.66) | PDE2A | |
| SCHEMBL11599924 | 0.67 | TSHR (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077853-B1 | NOVEL TRIFLUOROMETHYL BENZAL CHLORIDES AND PROCESS FOR THE PREPARATION THEREOF | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-03-13 | — | — | EP | disclosed |
| EP-0077853-A1 | Novel trifluoromethyl benzal chlorides and process for the preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4367348-A | Novel trifluoromethyl benzal chlorides and process for the preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |