Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972762 | 0.84 | TSHR (0.60) | TSHRPDE2ALMNACYP3A4MAPK1 | |
| SCHEMBL6644323 | 0.81 | PDE2A (0.65) | PDE2A | |
| SCHEMBL10969987 | 0.77 | TSHR (0.40) | TSHR | |
| SCHEMBL10970053 | 0.77 | PDE2A (0.42) | TSHRPDE2A | |
| SCHEMBL10969570 | 0.74 | TSHR (0.41) | TSHRPDE2A | |
| SCHEMBL10969460 | 0.74 | TSHR (0.41) | TSHR | |
| SCHEMBL1843312 | 0.74 | TSHR (1.00) | TSHRLMNATP53CYP3A4MAPK1 | |
| SCHEMBL29700271 | 0.72 | TP53 (0.58) | TSHRLMNATP53HTTCYP3A4 | |
| SCHEMBL7560420 | 0.72 | TP53 (0.58) | TSHRLMNATP53HTTCYP3A4 | |
| SCHEMBL8425257 | 0.70 | TSHR (0.65) | TSHRPDE2ALMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077853-B1 | NOVEL TRIFLUOROMETHYL BENZAL CHLORIDES AND PROCESS FOR THE PREPARATION THEREOF | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-03-13 | — | — | EP | disclosed |
| EP-0077853-A1 | Novel trifluoromethyl benzal chlorides and process for the preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4367348-A | Novel trifluoromethyl benzal chlorides and process for the preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| US-4201583-A | DRY PROCESS, NONSILVER PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1980-05-06 | — | — | US | disclosed |