SCHEMBL10970495

SCHEMBL10970495

CCOC(=O)[C@H](C)N(C(=O)CCl)c1c(C)cccc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.56
ALDH1A1 P00352 5/20 0.50
TP53 P04637 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
CYP3A4 P08684 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
PLA2G1B P04054 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ATG4B Q9Y4P1 1/20 0.46
THRB P10828 1/20 0.42
NPC1 O15118 1/20 0.39
NR1I2 O75469 1/20 0.38
MAPT P10636 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4659790 1.00 RORC (0.56) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL10983416 0.93 TP53 (0.57) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL10963681 0.93 TP53 (0.57) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL30601164 0.90 KMT2A (0.58) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL9781351 0.90 TP53 (0.54) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL395886 0.90 KMT2A (0.58) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL395887 0.90 KMT2A (0.58) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL11336341 0.88 THRB (0.46) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL11336340 0.88 THRB (0.46) RORCALDH1A1TP53TDP1CYP3A4
SCHEMBL11341272 0.86 RORC (0.45) RORCALDH1A1TP53TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0075167-B1 N-(1-ALKENYL)-CARBOXANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1985-02-13 EP disclosed
EP-0044482-B1 N-ALLENYLALKYL-ACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-11-16 EP disclosed
US-4385069-A Combating fungi with N-allenyl-acetanilides BAYER AKTIENGESELLSCHAFT (DE) 1983-05-24 US disclosed
EP-0017110-B1 N-DICHLOROACETYL-N-PHENYL-ALANIN(THIOL) ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-05-04 EP disclosed
EP-0075167-A2 N-(1-alkenyl)-carboxanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1983-03-30 EP disclosed
EP-0044482-A2 N-allenylalkyl-acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1982-01-27 EP disclosed
EP-0017110-A2 N-dichloroacetyl-N-phenyl-alanin(thiol) esters, process for their preparation and their use as fungicides BAYER AG (DE) 1980-10-15 EP disclosed