Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10961074 | 0.86 | POLB (0.51) | POLBKDM4EGAAHTTCYP3A4 | |
| SCHEMBL10978037 | 0.85 | CYP19A1 (0.46) | POLBKDM4EHTTCYP3A4THRB | |
| SCHEMBL11079034 | 0.85 | OPRM1 (0.40) | POLBCYP3A4KMT2AALDH1A1HPGD | |
| SCHEMBL10364855 | 0.83 | CYP19A1 (0.43) | POLBKDM4EHTTCYP3A4THRB | |
| SCHEMBL10972434 | 0.83 | CYP19A1 (0.43) | CYP3A4KMT2AALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL9480854 | 0.79 | KDM4E (0.44) | POLBKDM4EGAAHTTCYP3A4 | |
| Penconazole SCHEMBL24791 | 0.79 | CYP19A1 (0.41) | POLBKDM4EHTTCYP3A4THRB | |
| Penconazole SCHEMBL30015079 | 0.79 | CYP19A1 (0.41) | POLBKDM4EHTTCYP3A4THRB | |
| Penconazole SCHEMBL29416459 | 0.79 | CYP19A1 (0.41) | POLBKDM4EHTTCYP3A4THRB | |
| SCHEMBL10833443 | 0.79 | CYP19A1 (0.41) | POLBKDM4EHTTCYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148858-A1 | NOVEL TRIAZOLYL-SUBSTITUTED PROPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-07-24 | — | — | EP | disclosed |
| WO-1984004918-A1 | NOVEL TRIAZOLYL-SUBSTITUTED PROPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORP (US) | 1984-12-20 | — | — | WO | disclosed |
| EP-0127865-A1 | Novel triazolyl-substituted propane derivatives, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-12-12 | — | — | EP | disclosed |
| US-4482564-A | FUNGICIDES | SCHERING CORPORATION (US) | 1984-11-13 | — | — | US | disclosed |