Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926146 | 0.83 | CYP19A1 (0.51) | CYP19A1HTTPOLBKMT2AMEN1 | |
| SCHEMBL10970720 | 0.83 | CYP19A1 (0.53) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL11375336 | 0.82 | CYP19A1 (0.51) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL12532514 | 0.81 | CYP19A1 (0.50) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL9634892 | 0.81 | CYP19A1 (0.50) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL9790348 | 0.79 | LMNA (0.44) | CYP19A1HTTKDM4EPOLBLMNA | |
| SCHEMBL11610591 | 0.78 | CYP19A1 (0.47) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL9711370 | 0.78 | CYP19A1 (0.47) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL14370225 | 0.77 | CYP19A1 (0.46) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL11271596 | 0.77 | CYP19A1 (0.46) | CYP19A1HTTKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |