Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidino Acetate SCHEMBL28619528 | 0.89 | EGLN1 (0.43) | CTHEGLN1TDP1MAPTALDH1A1 | |
| Guanidino Acetate SCHEMBL33970 | 0.89 | — | — | |
| Guanidino Acetate SCHEMBL27413696 | 0.89 | EGLN1 (0.41) | CTHEGLN1TDP1MAPTALDH1A1 | |
| Guanidino Acetate SCHEMBL29087529 | 0.86 | — | — | |
| Guanidino Acetate SCHEMBL1098127 | 0.86 | — | — | |
| Guanidino Acetate SCHEMBL3331092 | 0.86 | — | — | |
| Guanidino Acetate SCHEMBL20531119 | 0.86 | — | — | |
| Guanidino Acetate SCHEMBL19458353 | 0.86 | EGLN1 (0.39) | CTHEGLN1TDP1MAPTALDH1A1 | |
| Guanidino Acetate SCHEMBL31316639 | 0.86 | — | — | |
| Guanidino Acetate SCHEMBL28133726 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703819-B2 | Use of guanidinoacetic acid (salts) combination with betaine and/or choline to produced an agent that is beneficial to health | ALZCHEM TROSTBERG GMBH (DE) | 2014-04-22 | — | — | US | disclosed |
| US-8536222-B2 | Addition compounds of guanidinoacetic acid | ALZCHEM AG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-20120238629-A1 | ADDITION COMPOUNDS OF GUANIDINOACETIC ACID | ALZCHEM TROSTBERG GMBH (DE) | 2012-09-20 | — | — | US | disclosed |
| US-8153685-B2 | For use in dietary supplements, animal feeds, and cosmetics; bioavailability | ALZCHEM TROSTBERG GMBH (DE) | 2012-04-10 | — | — | US | disclosed |
| CN-101132786-B | Salts, addition compounds and complex compounds of guanidinoacetic acid | ALZCHEM TROSTBERG GMBH | 2011-04-13 | — | — | CN | disclosed |
| US-20100055182-A1 | USE OF GUANIDINOACETIC ACID (SALTS) COMBINATION WITH BETAINE AND/OR CHOLINE TO PRODUCED AN AGENT THAT IS BENEFICIAL TO HEALTH | ALZCHEM TROSTBERG GMBH (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20090297656-A1 | Liquid Formulation Based On a Guanidinoacetic Acid Component | ALZCHEM TROSTBERG GMBH (DE) | 2009-12-03 | — | — | US | disclosed |
| US-20080161387-A1 | Salts, Addition Compounds and Complex Compounds of Guinadinoacetic Acid | ALZCHEM TROSTBERG GMBH (DE) | 2008-07-03 | — | — | US | disclosed |
| CN-101132786-A | Salts, addition compounds and complex compounds of guanidinoacetic acid | ALZCHEM TROSTBERG GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238629-A1 | ADDITION COMPOUNDS OF GUANIDINOACETIC ACID | GCDH, PCCA, PC | CTH 246/4885EGLN1 2586/4885TDP1 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.