Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10972147 | 1.00 | MEN1 (0.31) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10974488 | 0.99 | MEN1 (0.31) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10974491 | 0.99 | MEN1 (0.31) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| Bromide SCHEMBL10976436 | 0.75 | MEN1 (0.52) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| Bromide SCHEMBL11286161 | 0.70 | MAOA (0.33) | — | |
| Bromide SCHEMBL10972264 | 0.68 | INSR (0.47) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| Bromide SCHEMBL10972261 | 0.68 | INSR (0.47) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| Bromide SCHEMBL11318407 | 0.68 | MEN1 (0.56) | MEN1ALDH1A1KMT2ALMNAHTT | |
| Bromide SCHEMBL10974245 | 0.68 | MEN1 (0.56) | MEN1ALDH1A1KMT2ALMNAHTT | |
| SCHEMBL10974922 | 0.67 | INSR (0.48) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050558-B1 | PHOTOGRAPHIC EMULSIONS AND ELEMENTS CAPABLE OF FORMING DIRECT-POSITIVE IMAGES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-07-17 | — | — | EP | claimed |
| EP-0050558-B1 | PHOTOGRAPHIC EMULSIONS AND ELEMENTS CAPABLE OF FORMING DIRECT-POSITIVE IMAGES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-07-17 | — | — | EP | disclosed |
| EP-0050558-A2 | Photographic emulsions and elements capable of forming direct-positive images | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4306016-A | HETEROCYCLIC CYANINE DYE-LIKE NUCLEATING AGENTS | EASTMAN KODAK COMPANY (US) | 1981-12-15 | — | — | US | disclosed |