Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15167128 | 0.72 | CYP2A13 (0.43) | SMN1; SMN2CYP2A13KDM4EPOLBGAA | |
| SCHEMBL10473053 | 0.71 | IDO1 (0.44) | SMN1; SMN2CYP2A13KDM4EHTTTP53 | |
| SCHEMBL10446594 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2A13KDM4EPOLBGAA | |
| SCHEMBL22244 | 0.66 | TP53 (0.45) | SMN1; SMN2CYP2A13KDM4EPOLBHTT | |
| SCHEMBL28152640 | 0.65 | TP53 (0.44) | SMN1; SMN2CYP2A13KDM4EPOLBHTT | |
| SCHEMBL1515105 | 0.58 | HRH3 (0.54) | SMN1; SMN2CYP2A13HTTHSD17B10TP53 | |
| SCHEMBL17080613 | 0.57 | HRH3 (0.52) | SMN1; SMN2CYP2A13HTTHSD17B10KMT2A | |
| SCHEMBL4658999 | 0.57 | HRH3 (0.47) | SMN1; SMN2CYP2A13HTTHSD17B10KMT2A | |
| SCHEMBL11250877 | 0.57 | HRH3 (0.47) | SMN1; SMN2CYP2A13KDM4EPOLBHTT | |
| SCHEMBL31628992 | 0.56 | THRB (0.44) | SMN1; SMN2GAAHTTTP53HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092136-B1 | BENZOQUINONE DERIVATIVES AND PRODUCTION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1985-08-28 | — | — | EP | disclosed |