Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152640 | 0.98 | TP53 (0.44) | TP53SMN1; SMN2MAPTSTAT3HTT | |
| SCHEMBL15167128 | 0.81 | CYP2A13 (0.43) | TP53SMN1; SMN2MAPTSTAT3HTT | |
| SCHEMBL10446594 | 0.80 | SMN1; SMN2 (0.42) | TP53SMN1; SMN2MAPTSTAT3HTT | |
| SCHEMBL11243437 | 0.75 | STAT3 (0.44) | TP53SMN1; SMN2MAPTSTAT3HTT | |
| SCHEMBL10446465 | 0.75 | PKM (0.57) | SMN1; SMN2MAPTHTTCYP2A13KDM4E | |
| SCHEMBL10473053 | 0.73 | IDO1 (0.44) | TP53SMN1; SMN2MAPTHTTCYP2A13 | |
| SCHEMBL11250877 | 0.70 | HRH3 (0.47) | SMN1; SMN2MAPTHTTCYP2A13KDM4E | |
| SCHEMBL10446125 | 0.67 | SMN1; SMN2 (0.42) | TP53SMN1; SMN2MAPTHTTCYP2A13 | |
| SCHEMBL10972633 | 0.66 | SMN1; SMN2 (0.39) | TP53SMN1; SMN2HTTCYP2A13KDM4E | |
| SCHEMBL24498675 | 0.64 | CYP2A13 (0.41) | SMN1; SMN2MAPTHTTCYP2A13HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025587-A9 | PROCESS FOR THE MANUFACTURE OF TMHQ | DSM IP ASSETS B.V. (NL) | 2017-01-05 | — | — | WO | disclosed |
| EP-2609079-B1 | PROCESS FOR THE MANUFACTURE OF TMHQ | DSM IP ASSETS BV (NL) | 2015-05-06 | — | — | EP | disclosed |
| EP-2609079-B1 | PROCESS FOR THE MANUFACTURE OF TMHQ | DSM IP ASSETS BV (NL) | 2015-05-06 | — | — | EP | disclosed |
| US-8809591-B2 | Process for the manufacture of TMHQ | DSM IP ASSETS B.V. (NL) | 2014-08-19 | — | — | US | disclosed |
| US-8809591-B2 | Process for the manufacture of TMHQ | DSM IP ASSETS B.V. (NL) | 2014-08-19 | — | — | US | disclosed |
| US-20130211080-A1 | PROCESS FOR THE MANUFACTURE OF TMHQ | DSM IP ASSETS B.V. (NL) | 2013-08-15 | — | — | US | disclosed |
| US-20130211080-A1 | PROCESS FOR THE MANUFACTURE OF TMHQ | DSM IP ASSETS B.V. (NL) | 2013-08-15 | — | — | US | disclosed |
| EP-2609079-A1 | PROCESS FOR THE MANUFACTURE OF TMHQ | DSM IP Assets B.V. (NL) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025587-A1 | PROCESS FOR THE MANUFACTURE OF TMHQ | DSM IP ASSETS B.V. (NL) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130211080-A1 | PROCESS FOR THE MANUFACTURE OF TMHQ | POLQ, PNMT, TERT | TP53 2505/4885SMN1; SMN2 2258/4885MAPT 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.