SCHEMBL10972723

SCHEMBL10972723

CCOC(=O)CCOc1ccc(OC(=O)C(C)Oc2ccc(Oc3nc4ccc(Cl)cc4s3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
TP53 P04637 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
HIF1A Q16665 1/20 0.39
GMNN O75496 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
APEX1 P27695 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GAA P10253 1/20 0.39
PPARD Q03181 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10654126 0.90 PTPN1 (0.48) PTPN1L3MBTL1TP53TDP1LMNA
SCHEMBL11171379 0.89 PTPN1 (0.46) PTPN1L3MBTL1TP53TDP1LMNA
SCHEMBL18592608 0.85 PTPN1 (0.49) PTPN1L3MBTL1TP53TDP1LMNA
SCHEMBL161685 0.85 PTPN1 (0.49) PTPN1L3MBTL1TP53TDP1LMNA
SCHEMBL11174247 0.81 L3MBTL1 (0.40) L3MBTL1TP53TDP1LMNAMAPT
SCHEMBL11178604 0.80 PPARA (0.42) PTPN1L3MBTL1TP53TDP1LMNA
SCHEMBL10963928 0.80 MAPT (0.54) PTPN1L3MBTL1TP53LMNAMAPT
SCHEMBL10964437 0.79 GAA (0.44) PTPN1L3MBTL1TP53TDP1LMNA
SCHEMBL5933705 0.78 PTPN1 (0.47) PTPN1L3MBTL1TDP1LMNAMAPT
SCHEMBL10860939 0.78 MAPT (0.42) PTPN1L3MBTL1TP53TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4383850-A Benzthiazole or benzoxazole ethers, herbicidal compositions and use HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-17 US claimed
EP-0062905-B1 HETEROCYCLIC PHENYL ETHERS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-13 EP disclosed
US-4383850-A Benzthiazole or benzoxazole ethers, herbicidal compositions and use HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-17 US disclosed
EP-0062905-A1 Heterocyclic phenyl ethers, process for their production and herbicides containing them HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-20 EP disclosed