Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972723 | 0.90 | PTPN1 (0.41) | PTPN1TP53KMT2AKDM4ENR4A1 | |
| SCHEMBL11178604 | 0.89 | PPARA (0.42) | PTPN1TP53KMT2AKDM4ENR4A1 | |
| SCHEMBL8582569 | 0.86 | PPARD (0.52) | TP53TDP1L3MBTL1PPARDPPARA | |
| SCHEMBL8582571 | 0.80 | PPARA (0.46) | PTPN1KMT2ACSNK1DPPARAMAPT | |
| SCHEMBL161685 | 0.80 | PTPN1 (0.49) | PTPN1TP53KMT2AKDM4ETDP1 | |
| SCHEMBL18592608 | 0.80 | PTPN1 (0.49) | PTPN1TP53KMT2AKDM4ETDP1 | |
| SCHEMBL12667940 | 0.79 | TDP1 (0.48) | PTPN1KMT2AKDM4ETDP1PPARD | |
| SCHEMBL2167765 | 0.78 | HTT (0.60) | KMT2APPARDLMNA | |
| SCHEMBL4693607 | 0.78 | ACHE (0.53) | KMT2APPARDLMNAMAPTMEN1 | |
| SCHEMBL21991515 | 0.78 | TDP1 (0.50) | KMT2AKDM4ENR4A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157225-B1 | PROCESS FOR THE PRODUCTION OF BENZIMIDAZOLYL, BENZOXAZOLYL AND BENZOTHIAZOLYL OXYPHENOXYPROPIONATE DERIVATIVES | CASSELLA Aktiengesellschaft (DE) | 1988-01-20 | — | — | EP | disclosed |
| EP-0157225-A1 | Process for the production of benzimidazolyl, benzoxazolyl and benzothiazolyl oxyphenoxypropionate derivatives | CASSELLA Aktiengesellschaft (DE) | 1985-10-09 | — | — | EP | disclosed |