Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | HTR1A | P08908 | 3/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.67 |
| ▸ | DRD1 | P21728 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.67 |
| ▸ | HRH1 | P35367 | 3/20 | 0.67 |
| ▸ | DRD3 | P35462 | 3/20 | 0.67 |
| ▸ | MC3R | P41968 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859184 | 0.94 | KDM1A (0.94) | KDM1ALMNATP53CYP3A4HTR1A | |
| Perazine SCHEMBL29390464 | 0.91 | KDM1A (1.00) | KDM1ALMNATP53CYP3A4HTR1A | |
| Perazine SCHEMBL147165 | 0.91 | KDM1A (1.00) | KDM1ALMNATP53CYP3A4HTR1A | |
| Perazine SCHEMBL2237726 | 0.90 | KDM1A (0.97) | KDM1ALMNATP53CYP3A4HTR1A | |
| Perazine SCHEMBL6644457 | 0.90 | KDM1A (0.97) | KDM1ALMNATP53CYP3A4HTR1A | |
| SCHEMBL6865338 | 0.88 | KDM1A (0.75) | KDM1ASIGMAR1FPR2 | |
| SCHEMBL6867689 | 0.87 | KDM1A (0.74) | KDM1ASIGMAR1FPR2 | |
| SCHEMBL32690192 | 0.84 | KDM1A (0.75) | KDM1ASIGMAR1FPR2 | |
| SCHEMBL10136829 | 0.84 | KDM1A (0.75) | KDM1ASIGMAR1FPR2 | |
| Perazine SCHEMBL10531680 | 0.84 | KDM1A (0.84) | KDM1ALMNATP53CYP3A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60193985-A | — | — | None | — | — | JP | disclosed |
| JP-S60193985-A | ENZYME ACTIVITY INHIBITOR | KAKIUCHI SHIRO | 1985-10-02 | — | — | JP | disclosed |