Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014585 | 0.76 | DHODH (0.54) | MAPTALDH1A1MEN1KMT2APTPN7 | |
| SCHEMBL14808817 | 0.73 | ZAP70 (0.45) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL28827947 | 0.73 | KDM4E (0.33) | MAPTALDH1A1AKR1B1PTGS2HPGD | |
| SCHEMBL5381933 | 0.72 | KDM4E (0.49) | MAPTALDH1A1MEN1KMT2AAKR1B1 | |
| SCHEMBL11568973 | 0.72 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL4667117 | 0.71 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL14811606 | 0.70 | PDE4B (0.54) | PDE4B | |
| SCHEMBL361662 | 0.69 | CXCL8 (0.67) | BCAT2AKR1B1PTGS2CXCL8AKR1B10 | |
| SCHEMBL29622781 | 0.69 | CXCL8 (0.67) | BCAT2AKR1B1PTGS2CXCL8AKR1B10 | |
| SCHEMBL28397977 | 0.69 | BCAT2 (0.50) | MAPTALDH1A1BCAT2AKR1B1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053698-B1 | 5-AMINO-1-PHENYLPYRAZOLE-4-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |