Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 4/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981154 | 0.90 | ALOX5 (0.64) | PDGFRBALOX5MAPTKDM4EALDH1A1 | |
| SCHEMBL4508230 | 0.79 | PDGFRB (0.54) | PDGFRBALOX5MAPTKDM4EALDH1A1 | |
| SCHEMBL18285499 | 0.74 | KDM4E (0.97) | MAPTKDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL11078606 | 0.74 | ALOX5 (0.69) | PDGFRBALOX5MAPTKDM4EHPGD | |
| SCHEMBL14877399 | 0.73 | PDGFRB (0.56) | PDGFRBMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3052850 | 0.73 | FLT3 (0.73) | PDGFRB | |
| SCHEMBL14877401 | 0.73 | PDGFRB (0.57) | PDGFRBMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL26912673 | 0.72 | MAPT (0.59) | PDGFRBMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL26911783 | 0.72 | HTR1A (0.60) | PDGFRBMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL13458828 | 0.71 | KDM4E (0.74) | MAPTKDM4EALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061128-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM | STERLING DRUG INC. (US) | 1985-09-04 | — | — | EP | disclosed |
| US-4446321-A | COLOR FORMERS, CARBON-FREE DUPLICATION | STERLING DRUG INC. (US) | 1984-05-01 | — | — | US | disclosed |
| US-4363503-A | FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS | STERLING DRUG INC. (US) | 1982-12-14 | — | — | US | disclosed |
| EP-0061128-A1 | Pyridine compounds, process for their preparation and systems containing them | STERLING DRUG INC. (US) | 1982-09-29 | — | — | EP | disclosed |