Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718562 | 0.84 | HTT (0.62) | LMNARAB9AHTTMAPTALDH1A1 | |
| Quizalofop Ethyl Ester SCHEMBL9139248 | 0.84 | MAPT (0.67) | LMNARAB9AHTTMAPTALDH1A1 | |
| Quizalofop-P-Ethyl SCHEMBL53466 | 0.84 | MAPT (0.67) | LMNARAB9AHTTMAPTALDH1A1 | |
| Quizalofop-P-Ethyl SCHEMBL29474422 | 0.84 | MAPT (0.67) | LMNARAB9AHTTMAPTALDH1A1 | |
| SCHEMBL10973495 | 0.84 | ALDH1A1 (0.51) | LMNARAB9AHTTMAPTALDH1A1 | |
| Quizalofop Ethyl Ester SCHEMBL30406 | 0.84 | MAPT (0.67) | LMNARAB9AHTTMAPTALDH1A1 | |
| SCHEMBL8508358 | 0.84 | ALDH1A1 (0.51) | LMNARAB9AHTTMAPTALDH1A1 | |
| Quizalofop-P-Ethyl SCHEMBL23045019 | 0.83 | MAPT (0.66) | LMNARAB9AHTTMAPTALDH1A1 | |
| Quizalofop Ethyl Ester SCHEMBL23045020 | 0.83 | MAPT (0.66) | LMNARAB9AHTTMAPTALDH1A1 | |
| SCHEMBL10848461 | 0.82 | HTT (0.58) | LMNARAB9AHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023785-B1 | QUINOXALINYLOXYPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1985-04-03 | — | — | EP | disclosed |
| EP-0023785-A2 | Quinoxalinyloxyphenoxyalkane carboxylic acid derivatives, their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-02-11 | — | — | EP | disclosed |