Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17088269 | 0.81 | POLB (0.61) | PLAUALDH1A1MAPTPOLBGAA | |
| SCHEMBL3282776 | 0.80 | MEN1 (0.61) | PLAUALDH1A1MAPTPOLBGAA | |
| SCHEMBL3282773 | 0.80 | MEN1 (0.61) | PLAUALDH1A1MAPTPOLBGAA | |
| Sulfuric Acid SCHEMBL28654341 | 0.77 | CA1 (0.62) | ALDH1A1MAPK1TDP1LMNAF2 | |
| SCHEMBL17149472 | 0.76 | PLAU (0.57) | PLAUALDH1A1MAPTPOLBGAA | |
| SCHEMBL8538545 | 0.75 | MAPT (0.70) | PLAUALDH1A1MAPTPOLBGAA | |
| SCHEMBL28044369 | 0.75 | MAPT (0.70) | PLAUALDH1A1MAPTPOLBGAA | |
| SCHEMBL5305524 | 0.75 | MAPT (0.70) | PLAUALDH1A1MAPTPOLBGAA | |
| SCHEMBL4278062 | 0.75 | MAPT (0.70) | PLAUALDH1A1MAPTPOLBGAA | |
| SCHEMBL3428191 | 0.74 | MAPT (0.64) | PLAUALDH1A1MAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073000-B1 | METHOD OF MAKING ARYLHYDRAZINE-N-SULPHONIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-26 | — | — | EP | disclosed |
| US-4515940-A | REACTING ARYLDIAZONIUM SALTS WITH ALKALI OR ALKALINE EARTH METAL SULFITES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |
| US-4504424-A | HYDROGENATION OF ARYLAZOSULFONATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-12 | — | — | US | disclosed |
| EP-0068338-B1 | Process for preparing phenyldiazosulphonates | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-12 | — | — | EP | disclosed |
| EP-0073000-A2 | Method of making arylhydrazine-N-sulphonic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-02 | — | — | EP | disclosed |
| EP-0068338-A1 | Process for preparing phenyldiazosulphonates | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |