Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282776 | 0.86 | MEN1 (0.61) | PLAUNOS1ALDH1A1MEN1MAPT | |
| SCHEMBL3282773 | 0.86 | MEN1 (0.61) | PLAUNOS1ALDH1A1MEN1MAPT | |
| SCHEMBL15922 | 0.81 | ALDH1A1 (0.75) | PLAUNOS1ALDH1A1CA12CA2 | |
| SCHEMBL15923 | 0.81 | ALDH1A1 (0.75) | PLAUNOS1ALDH1A1CA12CA2 | |
| Hydrochloric Acid SCHEMBL30872195 | 0.79 | ALDH1A1 (0.72) | PLAUNOS1ALDH1A1CA12CA2 | |
| SCHEMBL27462114 | 0.79 | ALDH1A1 (0.64) | PLAUNOS1ALDH1A1CA12CA1 | |
| SCHEMBL10092679 | 0.78 | MEN1 (0.53) | PLAUNOS1ALDH1A1MEN1MAPT | |
| SCHEMBL270426 | 0.78 | MEN1 (0.66) | PLAUNOS1ALDH1A1MEN1MAPT | |
| SCHEMBL270425 | 0.78 | MEN1 (0.66) | PLAUNOS1ALDH1A1MEN1MAPT | |
| SCHEMBL29588234 | 0.78 | MEN1 (0.66) | PLAUNOS1ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260027213-A1 | EPICARDIAL-DERIVED PARACRINE FACTORS FOR REPAIRING CARDIAC TISSUE | REGENCOR INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-20250205306-A1 | USE OF FOLLISTATIN-LIKE 1 (FSTL1) IN CARDIOMETABOLIC HEART FAILURE | REGENCOR, INC. | 2025-06-26 | — | — | US | disclosed |
| EP-4499125-A1 | USE OF FOLLISTATIN-LIKE 1 (FSTL1) IN CARDIOMETABOLIC HEART FAILURE | Regencor, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119212718-A | Use of follistatin-like protein 1 (FSTL 1) in heart metabolic heart failure | 雷根科公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2023183933-A1 | USE OF FOLLISTATIN-LIKE 1 (FSTL1) IN CARDIOMETABOLIC HEART FAILURE | REGENCOR, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| EP-4088733-A1 | EPICARDIAL-DERIVED PARACRINE FACTORS FOR REPAIRING CARDIAC TISSUE | Regencor, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |
| EP-3280429-B1 | FSTL1 FOR USE IN REPAIRING CARDIAC TISSUE | REGENCOR INC (US) | 2022-06-01 | — | — | EP | disclosed |
| WO-2015154023-A1 | SUBSTITUTED SPIROCYDIC INHIBITORS OF AUTOTAXIN | X-RX DISCOVERY, INC. (US) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027213-A1 | EPICARDIAL-DERIVED PARACRINE FACTORS FOR REPAIRING CARDIAC TISSUE | TNNI3, TNNT2, FN1 | PLAU 734/4885NOS1 309/4885ALDH1A1 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.